A Majority of Adults Have Pre-Existing Antibody Reactivity to SARS-CoV-2: Study

A Majority of Adults Have Pre-Existing Antibody Reactivity to SARS-CoV-2: Study

Most adults examined in a recent study have pre-existing antibody reactivity to SARS-CoV-2, even if they haven’t had COVID-19. Interestingly, the research by Majdoubi, Michalski et al demonstrated the existence of these cross-reactive antibodies as far back as May 2020. From the abstract:

“Using a highly sensitive multiplex assay and positive/negative thresholds established in infants in whom maternal antibodies have waned, we determined that more than 90% of uninfected adults showed antibody reactivity against the spike protein, receptor-binding domain (RBD), N-terminal domain (NTD), or the nucleocapsid (N) protein from SARS-CoV-2.”

We conclude that most adults display preexisting antibody cross-reactivity against SARS-CoV-2, which further supports investigation of how this may impact the clinical severity of COVID-19 or SARS-CoV-2 vaccine responses.

Share on facebook
Share on twitter
Share on linkedin
Share on email

Related Posts

COVID Kid Facts

Before you vaccinate your healthy kids with the COVID-19 vaccine, consider if you have all the information you need to give informed consent. COVID Kid

Till We Have Faces: An Analysis of COVID-19 and Public Policy

621 days since the declaration by the World Health Organization of a pandemic, this scholarly and comprehensive essay comes from Dr. Hindmarsh, a fellow of the Royal Historical Society and professor of history and theology in Vancouver, BC. As written by Dr. Steven Pelech in the foreword, “Dr. Hindmarsh has done a remarkable job in making this information accessible, and he accurately tracks the unfolding of the COVID-19 pandemic and the consequences of how societies have reacted to this threat so far.”